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Literature summary for 2.4.1.212 extracted from

  • Uchiyama, T.; Sakuta, T.; Kanayama, T.
    Regulation of hyaluronan synthases in mouse uterine cervix (2005), Biochem. Biophys. Res. Commun., 327, 927-932.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information progesterone activates the expression of HAS3, low-molecular-weight hyaluronan activates the expression of isozyme HAS1 Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
additional information interleukin-1beta augmented the expression of all 3 isozymes in the uterine cervix of pregnant mice, progesterone inhibited expression of isozymes HAS1 and HAS2 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus isozyme expression and regulation by interleukin-1beta, progesterone, and low-molecular-weight hyaluronan in pregnant mouse uterine cervix, overview ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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pregnant mice, 3 isozymes HAS1, HAS2, and HAS3
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Source Tissue

Source Tissue Comment Organism Textmining
cervical epithelium
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Mus musculus
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cervix
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Mus musculus
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fibroblast uterine cervical Mus musculus
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additional information isozyme expression profile in uterine cervix of pregnant mice Mus musculus
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uterus
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Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information isozyme expression and regulation by interleukin-1beta, progesterone, and low-molecular-weight hyaluronan in pregnant mouse uterine cervix, overview Mus musculus ?
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?

Synonyms

Synonyms Comment Organism
HAS
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Mus musculus