Literature summary for 2.4.1.212 extracted from

Goentzel, B.J.; Weigel, P.H.; Steinberg, R.A.
Recombinant human hyaluronan synthase 3 is phosphorylated in mammalian cells (2006), Biochem. J., 396, 347-354.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in COS-7 cells	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
extracellular	-	Homo sapiens	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O00219	recombinant	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	human HAS3 expressed in COS-7 cells is serine-phosphorylated. This phosphorylation can be enhanced by a number of effectors, most significantly by a membrane-permeable analogue of cAMP. Under non-stimulating conditions, the FLAGHAS3 is phosphorylated to a stoichiometry of approx. 0.11 in COS-7 cells and, following maximal stimulation with 8-(4-chlorophenylthio)-cAMP, phosphorylation is increased to approximately 0.32 mol of phosphate/mol of protein	Homo sapiens

Synonyms

Synonyms	Comment	Organism
Has3	-	Homo sapiens
hyaluronan synthase 3	-	Homo sapiens

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Release 2023.1 (January 2023)