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Literature summary for 2.4.1.214 extracted from

  • Kumar, A.; Torii, T.; Ishino, Y.; Muraoka, D.; Yoshimura, T.; Togayachi, A.; Narimatsu, H.; Ikenaka, K.; Hitoshi, S.
    The Lewis X-related alpha1,3-fucosyltransferase, Fut10, is required for the maintenance of stem cell populations (2013), J. Biol. Chem., 288, 28859-28868.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56700
-
x * 56700, FLAG-tagged enzyme, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-
neural stem cell
-
Mus musculus
-

Subunits

Subunits Comment Organism
? x * 56700, FLAG-tagged enzyme, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
alpha1,3-fucosyltransferase 10
-
Mus musculus
FUT10
-
Mus musculus

General Information

General Information Comment Organism
malfunction suppression of isoform Fut10 expression induces the differentiation of neural stem cells and embryonic stem cells. In addition, enzyme knockdown in the cortical ventricular zone of the embryonic brain impairs the radial migration of neural precursor cells Mus musculus
physiological function isoform Fut10 is required for the maintenance of stem cell populations. Enzyme overexpression enhances the self-renewal of neural stem cells Mus musculus