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Literature summary for 2.4.1.255 extracted from

  • Shi, J.; Sharif, S.; Ruijtenbeek, R.; Pieters, R.J.
    Activity based high-throughput screening for novel O-GlcNAc transferase substrates using a dynamic peptide microarray (2016), PLoS ONE, 11, e0151085.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
analysis peptide microarray approach to discover novel OGT substrates and study its specificity Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O15294
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
RBL-2 + UDP-GlcNAc acceptor RBL-2 is a key regulator of entry into cell division. Residue Ser420 is a possible O-GlcNAc site in RBL-2. Substitution of Ser 420 inhibits OGT activity Homo sapiens ? + UDP
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