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Literature summary for 2.4.1.275 extracted from

  • Guo, S.; Sato, T.; Shirane, K.; Furukawa, K.
    Galactosylation of N-linked oligosaccharides by human beta-1,4-galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cells (2001), Glycobiology, 11, 813-820.
    View publication on PubMed
Search for more literature for 2.4.1.275

Cloned(Commentary)

Cloned (Comment) Organism
expression in Sf-9 cells Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.105
-
 UDP-galactose pH 7.0, temperature not specified in the publication Homo sapiens
0.238
-
 4-nitrophenyl N-acetyl-1-thio-beta-D-glucosaminide pH 7.0, temperature not specified in the publication Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O60513
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no galactosylation of asialo, agalacto-human transferrin having biantennary complex-type oligosaccharides Homo sapiens ?
-
 ?
UDP-alpha-D-galactose + 4-nitrophenyl N-acetyl-1-thio-beta-D-glucosaminide
-
 Homo sapiens UDP + 4-nitrophenyl 4-O-beta-D-galactopyranosiy-N-acetyl-1-thio-beta-D-glucosaminide
-
 ?
UDP-galactose + GlcNAc-beta-(1->6)-(GlcNAc-beta-(1->2))-Man-alpha-(1->3)-Man-beta-(1->)O(CH2)8COOCH2-m-nitrophenol preferential galactosylation of the GlcNAc-beta-(1->6)-Man branch Homo sapiens UDP + Gal-alpha-(1->4)-GlcNAc-beta-(1->6)-(GlcNAc-beta-(1->2))-Man-alpha-(1->3)-Man-beta-(1->)O(CH2)8COOCH2-m-nitrophenol
-
 ?

Synonyms

Synonyms Comment Organism
beta-1,4-GalT IV
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function beta-1,4-GalTs II, III, IV, V, and VI are involved in the N-linked oligosaccharide biosynthesis cooperatively but not in a redundant manner with beta-1,4-GalT I within cells Homo sapiens