Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(3S,4S)-3-(1,2-dihydroxyethyl)-4-hydroxy-1-(2-phenylethyl)tetrahydrothiophenium chloride | sulfonium ion compound as analogue of the donor substrate, uridine diphosphategalactofuranose. The compound contains moieties that mimic both galactofuranose and uridine diphosphate domains, and carries a permanent positive charge to mimic the oxocarbenium ion-like transition state. About 60% inhibition at 4 mM | Mycobacterium tuberculosis | |
(3S,4S)-3-(1,2-dihydroxyethyl)-4-hydroxy-1-[2-(4-nitrophenyl)ethyl]tetrahydrothiophenium bromide | sulfonium ion compound as analogue of the donor substrate, uridine diphosphategalactofuranose. The compound contains moieties that mimic both galactofuranose and uridine diphosphate domains, and carries a permanent positive charge to mimic the oxocarbenium ion-like transition state. About 50% inhibition at 4 mM | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | O53585 | - |
- |
Mycobacterium tuberculosis ATCC 25618 | O53585 | - |
- |