Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and anaylsis, sequence comparisons | Danio rerio |
Protein Variants | Comment | Organism |
---|---|---|
additional information | knockdown of zebrafish beta-4GalT1 by two independent morpholino oligonucleotides results in embryos with a truncated anterior-posterior axis, as well as elongated somites and moderate defects in the patterning of the head mesenchyme, phenotype with the axial mesoderm of epiboly stage embryos being abnormally widened in beta-4GalT1 morphants, indicative of abnormal convergent extension, laminin isolated from beta-4GalT1 morphant embryos is poorly galactosylated, activity is restored by injection of wild-type enzyme mRNA, overview | Danio rerio |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-galactose + laminin | Danio rerio | - |
UDP + beta-1,4-D-galactosyl-laminin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | the enzyme is maternally loaded and expressed throughout development, overview | Danio rerio | - |
oocyte | - |
Danio rerio | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Danio rerio |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-galactose + laminin | - |
Danio rerio | UDP + beta-1,4-D-galactosyl-laminin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta1,4-galactosyltransferase I | - |
Danio rerio |
beta4GalT1 | - |
Danio rerio |