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Literature summary for 2.4.1.38 extracted from

  • Yan, M.; Xia, C.; Niu, S.; Shao, X.; Cheng, C.; Zhao, J.; Shen, A.
    The role of TNF-alpha and its receptors in the production of beta-1,4 galactosyltransferase I and V mRNAs by rat primary astrocytes (2007), J. Mol. Neurosci., 33, 155-162.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information lipopolysaccharide stimulation of astrocytes induces the enzyme expression, overview Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
additional information TNF-alpha and its receptors affect the expression of beta-1,4 galactosyltransferase I mRNA by rat primary astrocytes, downregulation of beta-1,4-GalT I mRNA expression by TNF-alpha stimulation, overview; TNF-alpha and its receptors affect the expression of beta-1,4 galactosyltransferase V mRNA by rat primary astrocytes, overview Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane beta-1,4-GalT I is a type II membrane-bound glycoprotein which occurs on the plasma membrane of different types of cells where it serves as a cell surface adhesion molecule Rattus norvegicus 5886
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus beta-1,4-GalT I is a type II membrane-bound glycoprotein, which occurs the plasma membrane of different types of cells where it serves as a cell surface adhesion molecule mediating various cell-cell and cell-matrix interactions such as sperm-egg binding, cell spreading, migration, and neurite outgrowth ?
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Rattus norvegicus P80225 beta-1,4 galactosyltransferase I
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Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
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Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte primary Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information beta-1,4-GalT I is a type II membrane-bound glycoprotein, which occurs the plasma membrane of different types of cells where it serves as a cell surface adhesion molecule mediating various cell-cell and cell-matrix interactions such as sperm-egg binding, cell spreading, migration, and neurite outgrowth Rattus norvegicus ?
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?

Synonyms

Synonyms Comment Organism
beta-1,4 galactosyltransferase I
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Rattus norvegicus
beta-1,4 galactosyltransferase V
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Rattus norvegicus
beta-1,4-GalT I
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Rattus norvegicus
beta-1,4-GalT V
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Rattus norvegicus
GalTase
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Rattus norvegicus
More the enzyme belongs to the family of beta-1,4-galactosyltransferases, beta-1,4-GalTs Rattus norvegicus