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Literature summary for 2.4.1.38 extracted from

  • Tokuda, N.; Numata, S.; Li, X.; Nomura, T.; Takizawa, M.; Kondo, Y.; Yamashita, Y.; Hashimoto, N.; Kiyono, T.; Urano, T.; Furukawa, K.; Furukawa, K.
    beta4GalT6 is involved in the synthesis of lactosylceramide with less intensity than beta4GalT5 (2013), Glycobiology, 23, 1175-1183.
    View publication on PubMed
Search for more literature for 2.4.1.38

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminylglycopeptide Mus musculus
-
 UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminylglycopeptide
-
 Mus musculus UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide
-
 ?

Synonyms

Synonyms Comment Organism
beta-1,4-GalT5 isoform Mus musculus
beta-1,4-GalT6 isoform Mus musculus
beta1,4-galactosyltransferase
-
 Mus musculus

General Information

General Information Comment Organism
malfunction gene silencing of isoform beta4GalT5 results in the marked reduction in lactosylceramide synthase activity Mus musculus
metabolism the isoform beta4GalT6 plays a role as lactosylceramide synthase, while isoform beta4GalT5 acts as a main enzyme for lactosylceramide biosynthesis Mus musculus