Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.62 extracted from

  • Basu, S.; Kaufman, B.; Roseman, S.
    Conversion of Tay-Sachs ganglioside to monosialoganglioside by brain uridine diphosphate D-galactose: glycolipid galactosyltransferase (1965), J. Biol. Chem., 240, 4115-4117.
    View publication on PubMed
Search for more literature for 2.4.1.62

Inhibitors

Inhibitors Comment Organism Structure
EDTA complete inhibition Gallus gallus
EDTA complete inhibition Rattus norvegicus
EDTA complete inhibition Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
particle-bound
-
 Gallus gallus
-
-
particle-bound
-
 Rattus norvegicus
-
-
particle-bound
-
 Sus scrofa
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ required, Co2+ is 20% as effective as Mn2+ Gallus gallus
Mn2+ required, Co2+ is 20% as effective as Mn2+ Rattus norvegicus
Mn2+ required, Co2+ is 20% as effective as Mn2+ Sus scrofa
additional information
-
 Gallus gallus
additional information
-
 Sus scrofa
additional information no activation by Mg2+ Rattus norvegicus
additional information no activation Ca2+ Rattus norvegicus
additional information no activation Zn2+ Rattus norvegicus
additional information no activation Ni2+, Cu2+ Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
 embryonic
-
Rattus norvegicus
-
-
-
Sus scrofa
-
 fetus
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Gallus gallus
-
brain
-
 Rattus norvegicus
-
brain
-
 Sus scrofa
-

Storage Stability

Storage Stability Organism
-20°C, several months Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine best acceptor Gallus gallus UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine i.e. GM1 ganglioside or monosialoganglioside ?
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine best acceptor Rattus norvegicus UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine i.e. GM1 ganglioside or monosialoganglioside ?
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine best acceptor Sus scrofa UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine i.e. GM1 ganglioside or monosialoganglioside ?
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine i.e. GM2 or Tay-Sachs ganglioside Gallus gallus UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine i.e. GM1 ganglioside or monosialoganglioside ?
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine i.e. GM2 or Tay-Sachs ganglioside Rattus norvegicus UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine i.e. GM1 ganglioside or monosialoganglioside ?
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine i.e. GM2 or Tay-Sachs ganglioside Sus scrofa UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine i.e. GM1 ganglioside or monosialoganglioside ?