Literature summary for 2.4.1.65 extracted from

Morais, V.A.; Costa, J.
Stable expression of recombinant human alpha3/4 fucosyltransferase III in Spodoptera frugiperda Sf9 cells (2003), J. Biotechnol., 106, 69-75.

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Application

Application	Comment	Organism
molecular biology	the stable system using the expression vector pIB/Vf-His-TOPO constitutes an advance for the large scale expression of glycosyltransferases and possibly other glycoproteins in insect cells	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Spodoptera frugiperda SF-9 cells, the secreted activity SFT3 increases until the 6th day of culture when it reaches the value 1.9 mU x 10e-6 cells and 13.4 mg/l, whereas only 5% of activity is retained inside the cells	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
soluble	-	Homo sapiens	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GDP-fucose + Gal-beta-1,3GlcNAc-O-(CH2)3NHCO(CH2)5NH-biotin	-	Homo sapiens	GDP + Gal-beta-1,3(Fuc-alpha-1,4)GlcNAc-O-(CH2)3NHCO(CH2)5NH-biotin	-	?

Synonyms

Synonyms	Comment	Organism
alpha-3/4 fucosyltransferase	-	Homo sapiens
FT3	-	Homo sapiens
SFT3	secretory soluble form of FT3	Homo sapiens

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Release 2023.1 (January 2023)