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Literature summary for 2.4.1.66 extracted from
- Recruitment of matrix metalloproteinase-9 (MMP-9) to the fibroblast cell surface by lysyl hydroxylase 3 (lh3) triggers transforming growth factor-beta (TGF-beta) activation and fibroblast differentiation (2015), J. Biol. Chem., 290, 13763-13778.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryonic fibroblast | - |
Homo sapiens | - |
| MRC-5 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme displays lysyl hydroxylase as well as galactosyl- and glucosyltransferase activity | Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LH3 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | fibroblast cell surface recruitment of matrix metalloproteinase-9 via its fibronectin-like domain by lysyl hydroxylase 3 induces transforming growth factor-beta activation and myofibroblast differentiation | Homo sapiens |
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Release 2023.1 (January 2023)
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