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Literature summary for 2.4.1.69 extracted from
- GDP-L-fucose:lactose fucosyltransferase from mammary gland (1966), Methods Enzymol., 8, 351-353.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| GDP-D-mannose | stimulates | Canis lupus familiaris |  |
| GTP | stimulates | Canis lupus familiaris | |
| UDP | stimulates | Canis lupus familiaris | |
| UDP-D-glucose | stimulates | Canis lupus familiaris | |
| UDP-N-acetyl-D-glucosamine | stimulates | Canis lupus familiaris | |
| UTP | stimulates | Canis lupus familiaris | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 7 | - |
lactose | - |
Canis lupus familiaris | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Canis lupus familiaris | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Canis lupus familiaris | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| mammary gland | - |
Canis lupus familiaris | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, enzyme loses half of its original activity after 36 h | Canis lupus familiaris |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GDP-L-fucose + beta-D-galactosyl-R | - |
Canis lupus familiaris | GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R | - |
? | |
| GDP-L-fucose + lactose | - |
Canis lupus familiaris | GDP + fucosyllactose | - |
? | |
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Release 2023.1 (January 2023)
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