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Literature summary for 2.4.1.69 extracted from
- Biosynthesis of intestinal glycoprotein: a study of an (1 lead to 2) fucosyltransferase in rat small intestinal mucosa (1971), Arch. Biochem. Biophys., 147, 753-761.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Rattus norvegicus |  |
| CTP | - |
Rattus norvegicus | |
| UTP | - |
Rattus norvegicus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| GDP | competitive | Rattus norvegicus | |
| GMP | competitive | Rattus norvegicus | |
| GTP | competitive | Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0011 | - |
GDP-L-fucose | reaction with porcine submaxillary mucin or intestinal glycoprotein | Rattus norvegicus | |
| 0.0014 | - |
GDP-L-fucose | reaction with desialized fetuin | Rattus norvegicus | |
| 0.0016 | - |
GDP-L-fucose | reaction with lactose | Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | dependent on | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| small intestine mucosa | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GDP-L-fucose + beta-D-galactosyl-R | - |
Rattus norvegicus | GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R | - |
? | |
| GDP-L-fucose + beta-methyl-D-galactopyranoside | - |
Rattus norvegicus | GDP + alpha-L-fucosyl-1,2-beta-methyl-D-galactopyranoside | - |
? | |
| GDP-L-fucose + fetuin | - |
Rattus norvegicus | GDP + alpha-L-fucosyl-1,2-fetuin | - |
? | |
| GDP-L-fucose + intestinal glycoprotein | - |
Rattus norvegicus | GDP + alpha-L-fucosyl-1,2-intestinal glycoprotein | - |
? | |
| GDP-L-fucose + lacto-N-biose 1 | - |
Rattus norvegicus | GDP + L-Fucalpha(1-2)Galbeta(1-3)GlcNAc | - |
? | |
| GDP-L-fucose + lacto-N-fucopentaose II | - |
Rattus norvegicus | GDP + ? | - |
? | |
| GDP-L-fucose + lacto-N-tetraose | - |
Rattus norvegicus | GDP + lacto-N-fucopentaose I | - |
? | |
| GDP-L-fucose + lactose | - |
Rattus norvegicus | GDP + fucosyllactose | - |
? | |
| GDP-L-fucose + N-acetyllactosamine | - |
Rattus norvegicus | GDP + alpha-L-fucosyl-1,2-N-acetyllactosamine | - |
? | |
| GDP-L-fucose + porcine submaxillary mucin | - |
Rattus norvegicus | GDP + alpha-L-fucosyl-1,2-porcine submaxillary mucin | - |
? | |
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