Activating Compound | Comment | Organism | Structure |
---|---|---|---|
CHAPSO | the truncated enzyme is optimally activated by CHAPSO, showing little activity in absence | Rattus norvegicus | |
Triton CF-54 | the native and the recombinant full-length enzyme display significant activity in absence of detergent or phospholipid and are optimally activated in presence of Triton CF-54 detergent | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
full length enzyme and truncated enzyme missing the first 27 amino acid residues from the N-terminus, comprising the cytoplasmic and transmembrane domains | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | recombinant full length enzyme has a specific activity over 80fold higher than the truncated enzyme missing the first 27 amino acid residues from the N-terminus, comprising the cytoplasmic and transmembrane domains. The native and the recombinant full-length enzyme display significant activity in absence of detergent or phospholipid and are optimally activated in presence of Triton CF-54 detergent. The truncated enzyme is optimally activated by CHAPSO, showing littel activity in absence | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q10984 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
H35 cell | - |
Rattus norvegicus | - |
hepatoma cell | e.g. hepatoma H35 cells, the enzyme is induced during early stages of chemical hepatocarcinogenesis in parenchymal cells of Fischer 344 rats fed a diet supplemented with 0.03% N-2-acetylaminofluorene, undetectable in normal liver tissue | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-L-fucose + beta-D-galactosyl-R | - |
Rattus norvegicus | GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R | - |
? | |
additional information | the enzyme shows a strong preference for terminal Galbeta1, 3GalNAc structures | Rattus norvegicus | ? | - |
? |