Literature summary for 2.4.1.69 extracted from

Chandrasekaran, E.V.; Xue, J.; Piskorz, C.; Locke, R.D.; Toth, K.; Slocum, H.K.; Matta, K.L.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities (2007), J. Cancer Res. Clin. Oncol., 133, 599-611.

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Application

Application	Comment	Organism
medicine	tumor marker for human gastric cancer, down regulation of alpha1,2-fucosyltransferase activity is associated with human gastric tumorigenesis	Homo sapiens
medicine	it is shown that human alpha(1,2)-fucosyltransferase activity is remarkably decreased (40-90%) in human gastric cancer and may serve as a potential tumor marker	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mn2+	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
gastric cancer cell	down regulation of alpha1,2-fucosyltransferase activity is associated with human gastric tumorigenesis	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GDP-fucose + Galbeta-O-Bn	-	Homo sapiens	GDP + L-Fucalpha(1-2)Galbeta-O-Bn	-	?

Synonyms

Synonyms	Comment	Organism
alpha (1,2)fucosyltransferase	-	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.5	-	assay at	Homo sapiens

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Release 2023.1 (January 2023)