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Literature summary for 2.4.1.69 extracted from

  • Zeyland, J.; Wozniak, A.; Gawronska, B.; Juzwa, W.; Jura, J.; Nowak, A.; S?omski, R.; Smorag, Z.; Szalata, M.; Mazurek, U.; Lipinski, D.
    Double transgenic pigs with combined expression of human alpha1,2-fucosyltransferase and alpha-galactosidase designed to avoid hyperacute xenograft rejection (2014), Arch. Immunol. Ther. Exp., 62, 411-422.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine co-expression of the enzyme with 1,3-galactosyltransferase leads to a considerable reduction of the alpha-Gal antigen level on the surface of cells and a decrease of xenotransplant immunogenicity Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sus scrofa Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P19526
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-

Synonyms

Synonyms Comment Organism
alpha1,2-fucosyltransferase
-
Homo sapiens