Literature summary for 2.4.1.B62 extracted from

Kim, H.; Kim, W.H.; Kim, M.; Jeong, S.H.; Lee, K.
Evaluation of a rapid membrane enzyme immunoassay for the simultaneous detection of glutamate dehydrogenase and toxin for the diagnosis of Clostridium difficile infection (2014), Ann. Lab. Med., 34, 235-239.

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Application

Application	Comment	Organism
medicine	evaluation of comercially available rapid membrane enzyme immunoassays that use either glutamate dehydrogenase antigen or toxin A and B detection or a combination of both. Sensitivity, specificity, positive predictive values, and negative predictive values are 63.6%, 98.0%, 76.1%, and 96.4%, respectively, for the CD COMPLETE-toxin assay and 75.5%, 97.4%, 72.5%, and 97.8%, respectively, for the VIDAS CDAB assay. In comparison to the enriched Clostridium difficile cultures, the sensitivity, specificity, positive predictive values, and negative predictive values for the CD COMPLETE-GDH assay are 91.0%, 92.4%, 70.5%, and 98.1%, respectively. The CD COMPLETE assay is a reliable method for the diagnosis of Costridium difficile infection and provides greater sensitivity than toxin enzyme immunoassay alone	Clostridioides difficile

Organism

Organism	UniProt	Comment	Textmining
Clostridioides difficile	-	-	-

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Release 2023.1 (January 2023)