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Literature summary for 2.4.1.B62 extracted from
- Purification and characterisation of toxin B from a strain of Clostridium difficile that does not produce toxin A (1991), J. Med. Microbiol., 35, 40-44.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 43000 | - |
x * 220000, x * 43000, SDS-PAGE | Clostridioides difficile |
| 105000 | - |
and 220000, PAGE of toxin B | Clostridioides difficile |
| 220000 | - |
and 105000, PAGE. The 220000 Da subunit of toxin B from strain 8864 migrates slightly faster than the subunit from strain 10463 | Clostridioides difficile |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridioides difficile | - |
strain does not produce toxin A | - |
| Clostridioides difficile 8864 | - |
strain does not produce toxin A | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| purification of toxin B from strain 8864 that does not produce toxin A | Clostridioides difficile |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| multimer | x * 220000, x * 43000, SDS-PAGE | Clostridioides difficile |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | strain 8864 which does not produce toxin A produces a modified toxin B. After treatment of fibroblasts with toxin B from strain 10463, which produces both toxin A and toxin B, cells become rounded and highly arborised, giving the characteristic actinomorphic appearance. With the toxin B from strain 8864, no arborisation of cells occurrs but there is rounding and significant detachment | Clostridioides difficile |
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