Literature summary for 2.4.2.1 extracted from

Caceres, R.A.; Timmers, L.F.; Pauli, I.; Gava, L.M.; Ducati, R.G.; Basso, L.A.; Santos, D.S.; de Azevedo, W.F.
Crystal structure and molecular dynamics studies of human purine nucleoside phosphorylase complexed with 7-deazaguanine (2010), J. Struct. Biol., 169, 379-388.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with 7-deazaguanine, to 2.75 A resolution. Two intermolecular hydrogen bonds involve the residues Glu201 and Asn243	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
7-Deazaguanine	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P00491	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.2	-	7-Deazaguanine	pH 7.6, 25°C	Homo sapiens

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Release 2023.1 (January 2023)