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Literature summary for 2.4.2.1 extracted from

  • Stuer-Lauridsen, B.; Nygaard, P.
    Purine salvage in two halophilic archaea: characterization of salvage pathways and isolation of mutants resistant to purine analogs (1998), J. Bacteriol., 180, 457-463.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Halobacterium salinarum
-
-
-
Haloferax volcanii
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
10
-
substrate adenosine, crude cell extract, pH 7.5, temperature not specified in the publication Halobacterium salinarum
370
-
substrate guanosine, crude cell extract, pH 7.5, temperature not specified in the publication Halobacterium salinarum
2630
-
substrate adenosine, crude cell extract, pH 7.5, temperature not specified in the publication Haloferax volcanii
2890
-
substrate inosine, crude cell extract, pH 7.5, temperature not specified in the publication Halobacterium salinarum
3740
-
substrate inosine, crude cell extract, pH 7.5, temperature not specified in the publication Haloferax volcanii
5420
-
substrate guanosine, crude cell extract, pH 7.5, temperature not specified in the publication Haloferax volcanii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenosine + phosphate
-
Halobacterium salinarum adenine + alpha-D-ribose 1-phosphate
-
?
adenosine + phosphate
-
Haloferax volcanii adenine + alpha-D-ribose 1-phosphate
-
?
guanosine + phosphate
-
Halobacterium salinarum guanine + alpha-D-ribose 1-phosphate
-
?
guanosine + phosphate
-
Haloferax volcanii guanine + alpha-D-ribose 1-phosphate
-
?
inosine + phosphate
-
Halobacterium salinarum hypoxanthine + alpha-D-ribose 1-phosphate
-
?
inosine + phosphate
-
Haloferax volcanii hypoxanthine + alpha-D-ribose 1-phosphate
-
?

General Information

General Information Comment Organism
metabolism comparison of growth characteristics including intracellular protein levels, RNA content, and nucleotide pool sizes between the extreme halophile Halobacterium halobium and the moderate halophile Haloferax volcanii. The differences in the metabolism of purine bases and nucleosides and the sensitivity to purine analogs between the two halobacteria are reflected in differences in purine enzyme levels Halobacterium salinarum
metabolism comparison of growth characteristics including intracellular protein levels, RNA content, and nucleotide pool sizes between the extreme halophile Halobacterium halobium and the moderate halophile Haloferax volcanii. The differences in the metabolism of purine bases and nucleosides and the sensitivity to purine analogs between the two halobacteria are reflected in differences in purine enzyme levels Haloferax volcanii