Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | no inhibition by SH-group reagents | Homo sapiens | |
additional information | no inhibition by SH-group reagents | Plasmodium falciparum | |
PCMB | 0.01 mM, complete inhibition | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Homo sapiens | - |
- |
soluble | - |
Plasmodium falciparum | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | Homo sapiens | final steps in biosynthesis of UMP | orotidine 5'-phosphate + diphosphate | - |
? | |
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | Plasmodium falciparum | final steps in biosynthesis of UMP | orotidine 5'-phosphate + diphosphate | - |
? | |
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | Plasmodium falciparum FCB | final steps in biosynthesis of UMP | orotidine 5'-phosphate + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Plasmodium falciparum | - |
FCB strain | - |
Plasmodium falciparum FCB | - |
FCB strain | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Storage Stability | Organism |
---|---|
4°C, t1/2: 1.5 days | Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme from mammals is a bifunctional polypeptide, it also catalyzes the reaction listed as EC 4.1.1.23 | Homo sapiens | ? | - |
? | |
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Plasmodium falciparum | orotidine 5'-phosphate + diphosphate | - |
? | |
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | final steps in biosynthesis of UMP | Homo sapiens | orotidine 5'-phosphate + diphosphate | - |
? | |
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | final steps in biosynthesis of UMP | Plasmodium falciparum | orotidine 5'-phosphate + diphosphate | - |
? | |
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Plasmodium falciparum FCB | orotidine 5'-phosphate + diphosphate | - |
? | |
orotate + 5-phospho-alpha-D-ribose 1-diphosphate | final steps in biosynthesis of UMP | Plasmodium falciparum FCB | orotidine 5'-phosphate + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | - |
Plasmodium falciparum |
More | enzyme from mammals is a bifunctional polypeptide, it also catalyzes the reaction listed as EC 4.1.1.23 | Homo sapiens |