ADP |
50% inhibition of wild-type, S283A, K305Q, R307Q and S347A mutant enzyme at 4.7 mM, 24 mM, 31 mM, 28 mM and 8.1 mM respectively |
Bacillus subtilis |
|
AMP |
50% inhibition of wild-type, S283A, K305Q, R307Q and S347A mutant enzyme at 0.9 mM, 6.1 mM, 2.5 mM, 2.6 mM and 1.5 mM respectively |
Bacillus subtilis |
|
GMP |
50% inhibition of wild-type, S283A, K305Q, R307Q and S347A mutant enzyme at 9.4 mM, 6.6 mM, 50 mM, 50 mM and 145 mM respectively |
Bacillus subtilis |
|
IMP |
50% inhibition of wild-type and S347A mutant enzyme at 26 mM and 41 mM respectively |
Bacillus subtilis |
|
additional information |
strong synergistic inhibition with ADP and GMP |
Bacillus subtilis |
|