Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate | Homo sapiens | - |
L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q06203 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
lung adenocarcinoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate | - |
Homo sapiens | L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phosphoribosyl amidotransferase | - |
Homo sapiens |
PPAT | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | increased enzyme expression correlates with aggressive lung cancer. L-glutamine induces enzyme expression | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is critical for lung cancer cell proliferation and invasion | Homo sapiens |