Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ag+ | 1 mM, complete inhibition | Sus scrofa | |
Al3+ | 1 mM, 82.8% inhibition | Sus scrofa | |
Ba2+ | 1 mM, 38.1% inhibition | Sus scrofa | |
Ca2+ | 1 mM, 34.9% inhibition | Sus scrofa | |
Cd2+ | 1 mM, 75.5% inhibition | Sus scrofa | |
Co2+ | 1 mM, 65.2% inhibition | Sus scrofa | |
Cr3+ | 1 mM, 46.4% inhibition | Sus scrofa | |
Cu2+ | 1 mM, 86.9% inhibition | Sus scrofa | |
Fe2+ | 1 mM, 61.5% inhibition | Sus scrofa | |
Fe3+ | 1 mM, 92.9% inhibition | Sus scrofa | |
Hg2+ | 1 mM, 99.9% inhibition | Sus scrofa | |
Mg2+ | 1 mM, 7.7% inhibition | Sus scrofa | |
Mn2+ | 1 mM, 80.3% inhibition | Sus scrofa | |
Ni2+ | 1 mM, 76.5% inhibition | Sus scrofa | |
Sr2+ | 47.6% inhibition | Sus scrofa | |
Zn2+ | 1 mM, 82.1% inhibition | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.12 | - |
quinolinate | - |
Sus scrofa | |
0.18 | - |
5-phospho-alpha-D-ribose 1-diphosphate | - |
Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cd2+ | can partially replace Mg2+ | Sus scrofa | |
Co2+ | can partially replace Mg2+ | Sus scrofa | |
Mg2+ | divalent cation required, Mg2+ is most effective at 1 mM | Sus scrofa | |
Zn2+ | can partially replace Mg2+ | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Sus scrofa | intermediary enzyme in the de novo NAD biosynthetic pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | intermediary enzyme in the de novo NAD biosynthetic pathway | Sus scrofa | ? | - |
? | |
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Sus scrofa | nicotinate D-ribonucleotide + diphosphate + CO2 | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.1 | - |
- |
Sus scrofa |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.2 | 7.8 | half maximal activity at pH 5.2 and pH 7.8 | Sus scrofa |