Cloned (Comment) | Organism |
---|---|
expression of MTAP in MTAP-deleted MCF-7 breast adenocarcinoma cells results in a significant reduction of ODC activity | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-methylthioadenosine + phosphate | Saccharomyces cerevisiae | the enzyme regulates ornithine decarboxylase by production of downstream metabolites. Tumor suppressor activity of MTAP may be due to its effect on ornithine decarboxylase activity | adenine + 5-methylthio-D-ribose 1-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-methylthioadenosine + phosphate | - |
Saccharomyces cerevisiae | adenine + 5-methylthio-D-ribose 1-phosphate | - |
? | |
5'-methylthioadenosine + phosphate | the enzyme regulates ornithine decarboxylase by production of downstream metabolites. Tumor suppressor activity of MTAP may be due to its effect on ornithine decarboxylase activity | Saccharomyces cerevisiae | adenine + 5-methylthio-D-ribose 1-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MTAP | - |
Saccharomyces cerevisiae |