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Literature summary for 2.4.2.30 extracted from
- Pseudomonas aeruginosa exoenzyme S, a bifunctional type-III secreted cytotoxin (2000), Int. J. Med. Microbiol., 290, 381-387.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + (ADP-D-ribosyl)n-acceptor | Pseudomonas aeruginosa | intracellular expression of the amino terminus of ExoS in eukaryotic cells stimulates actin reorganization without cytotoxicity, which involves small-molecular-weight GTPases of the Rho subfamily | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + (ADP-D-ribosyl)n-acceptor | intracellular expression of the amino terminus of ExoS in eukaryotic cells stimulates actin reorganization without cytotoxicity, which involves small-molecular-weight GTPases of the Rho subfamily | Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? | |
| NAD+ + (ADP-D-ribosyl)n-Ras | - |
Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-Ras | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| exoenzyme S | - |
Pseudomonas aeruginosa |
| ExoS | - |
Pseudomonas aeruginosa |
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Release 2023.1 (January 2023)
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