Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + (ADP-D-ribosyl)n-Ras | Pseudomonas aeruginosa | ADP-ribosylation of Ras at Arg41 disrupts Ras-Cdc25 interactions, which inhibits the rate-limiting step in Ras signal transduction, the activation of Ras by its guanine nucleotide exchange factor | nicotinamide + (ADP-D-ribosyl)n+1-Ras | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + (ADP-D-ribosyl)n-Ras | - |
Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-Ras | - |
? | |
NAD+ + (ADP-D-ribosyl)n-Ras | ADP-ribosylation of Ras at Arg41 disrupts Ras-Cdc25 interactions, which inhibits the rate-limiting step in Ras signal transduction, the activation of Ras by its guanine nucleotide exchange factor | Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-Ras | - |
? |
Synonyms | Comment | Organism |
---|---|---|
exoenzyme S | - |
Pseudomonas aeruginosa |