Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5'-O-trityl-inosine | IC50: 0.044 mM, reversible, noncompetitive inhibition with respect to thymidine and phosphate | Escherichia coli | |
5'-O-trityl-inosine | IC50: 0.067 mM, reversible, noncmpetitive | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Homo sapiens | P19971 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thymidine + phosphate | - |
Escherichia coli | thymine + 2-deoxy-D-ribose 1-phosphate | - |
? | |
thymidine + phosphate | - |
Homo sapiens | thymine + 2-deoxy-D-ribose 1-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Tpase | - |
Escherichia coli |
Tpase | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.039 | - |
5'-O-trityl-inosine | against thymidine | Escherichia coli | |
0.146 | - |
5'-O-trityl-inosine | against phosphate | Escherichia coli |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.044 | - |
IC50: 0.044 mM, reversible, noncompetitive inhibition with respect to thymidine and phosphate | Escherichia coli | 5'-O-trityl-inosine | |
0.067 | - |
IC50: 0.067 mM, reversible, noncmpetitive | Homo sapiens | 5'-O-trityl-inosine |