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Literature summary for 2.4.2.8 extracted from
- Gene expression and mRNA editing of serotonin receptor 2C in brains of HPRT gene knock-out mice, an animal model of Lesch-Nyhan disease (2009), J. Clin. Neurosci., 16, 1061-1063.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | generation of HPRT gene knock-out mice, the mutant mice show 55% increased expression of the serotonin receptor 2C, HTR2C, semiquantitative realtime RT-PCR expression analysis | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
gene HPRT | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HPRT | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | complete deficiency of hypoxanthine-guanine phosphoribosyltransferase causes the Lesch-Nyhan disease, a genetic disorder associated with motor and psychiatric disturbance and self-injurious behaviour, the role of serotonin receptor 2C, HTR2C, might be involved, overview | Mus musculus |
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Release 2023.1 (January 2023)
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