Inhibitors | Comment | Organism | Structure |
---|---|---|---|
K+ | slight inhibition at 0.1 M | Lactobacillus leichmannii | |
Na+ | slight inhibition at 0.1 M | Lactobacillus leichmannii |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0077 | - |
Uracil | - |
Lactobacillus leichmannii | |
0.67 | - |
2-Thiouracil | - |
Lactobacillus leichmannii |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Lactobacillus leichmannii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lactobacillus leichmannii | - |
strain ATCC 4797 | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0057 | - |
substrate 2-thiouracil | Lactobacillus leichmannii |
0.0067 | - |
substrate uracil | Lactobacillus leichmannii |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-thiouracil + 5-phospho-alpha-D-ribose 1-diphosphate | substrate is anti-thyroid drug | Lactobacillus leichmannii | 2-thio-5'-UMP + diphosphate | - |
? | |
uracil + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Lactobacillus leichmannii | UMP + diphosphate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Lactobacillus leichmannii |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | 6.5 | plateau, substrate uracil | Lactobacillus leichmannii |
7.5 | 8 | substrate 2-thiouracil | Lactobacillus leichmannii |
7.8 | - |
2-thiouracil | Lactobacillus leichmannii |