Any feedback?
Literature summary for 2.4.2.9 extracted from
- Non-invasive molecular and functional imaging of cytosine deaminase and uracil phosphoribosyltransferase fused with red fluorescence protein (2008), Acta Oncol., 47, 1211-1220.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | increased expression of UPRT may improve the antitumoral effect of 5-fluorouracil and 5-fluorocytosine, and thereby enhance the potential gene-directed enzyme prodrug therapy | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cytosine deaminase-UPRT-red fluorescence protein fusion proteins are expressed in Rattus norvegicus R-3327-AT cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q96BW1 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| uracil + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Homo sapiens | UMP + diphosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| UPRT | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
