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Literature summary for 2.4.99.17 extracted from

  • Grimm, C.; Ficner, R.; Sgraja, T.; Haebel, P.; Klebe, G.; Reuter, K.
    Crystal structure of Bacillus subtilis S-adenosylmethionine:tRNA ribosyltransferase-isomerase (2006), Biochem. Biophys. Res. Commun., 351, 695-701.
    View publication on PubMed
Search for more literature for 2.4.99.17

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop vapor diffusion method, using 100 mM Tris/HCl (pH 8.0), 200 mM (NH4)2SO4, 3 mM dithiothreitol, and 25-29% (w/v) PEG 4000 Bacillus subtilis

Inhibitors

Inhibitors Comment Organism Structure
Mg2+ millimolar inhibitor Bacillus subtilis
Mn2+ millimolar inhibitor Bacillus subtilis

Organism

Organism UniProt Comment Textmining
Bacillus subtilis O32054
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bacillus subtilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine34 in tRNA
-
 Bacillus subtilis L-methionine + adenine + epoxyqueuosine34 in tRNA
-
 ?

Synonyms

Synonyms Comment Organism
QueA
-
 Bacillus subtilis
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
-
 Bacillus subtilis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.7
-
-
 Bacillus subtilis

General Information

General Information Comment Organism
metabolism the enzyme is involved in the biosynthesis of the hypermodified tRNA nucleoside queuosine Bacillus subtilis