Literature summary for 2.5.1.15 extracted from

Eagon, R.G.; McManus, A.T.
Phosphanilic acid inhibits dihydropteroate synthase (1989), Antimicrob. Agents Chemother., 33, 1936-1938.

Inhibitors

Inhibitors	Comment	Organism
phosphanilic acid	28% inhibition at 2.0 mM, complete inhibition at 20 mM	Escherichia coli
phosphanilic acid	22% inhibition at 2.0 mM, 84% inhibition at 20 mM	Pseudomonas aeruginosa
Sulfadiazine	0.2 mM, complete inhibition	Escherichia coli
Sulfadiazine	0.2 mM, complete inhibition	Pseudomonas aeruginosa

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-
Pseudomonas aeruginosa	-	-	-

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Release 2023.1 (January 2023)