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Literature summary for 2.5.1.16 extracted from

  • Pegg, A.E.
    Inhibition of aminopropyltransferases (1983), Methods Enzymol., 94, 294-297.
    View publication on PubMed
Search for more literature for 2.5.1.16

Inhibitors

Inhibitors Comment Organism Structure
5'-ethylthioadenosine strong Rattus norvegicus
5'-methylthioadenosine strong Rattus norvegicus
5'-methylthiotubercidin in vivo and in vitro, strong Rattus norvegicus
alpha,omega-Diamines with 3 carbon atoms, at 0.25 mM, not at 2.5 mM substrate concentration Rattus norvegicus
cadaverine
-
 Rattus norvegicus
Cyclohexylamine
-
 Rattus norvegicus
additional information polyamines Rattus norvegicus
S-5'-Deoxyadenosyl(5')-2-methylthioethylamine prostate Rattus norvegicus
S-Adenosyl-1,8-diamino-3-methylthiooctane less efficient than the thioether Rattus norvegicus
S-Adenosyl-1,8-diamino-3-thiooctane prostate Rattus norvegicus
S-Adenosyl-3-thiopropylamine sulfone
-
 Rattus norvegicus
S-Adenosyl-4-methylthiobutyric acid
-
 Rattus norvegicus
S-Adenosyl-L-homocysteine sulfone
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-3-methylthio-1-propylamine + 1,4-diaminobutane Rattus norvegicus
-
 5'-methylthioadenosine + spermidine
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-(5')-3-methylthio-1-propylamine + 1,4-diaminobutane
-
 Rattus norvegicus 5'-methylthioadenosine + spermidine
-
 ?
S-adenosyl-3-methylthio-1-propylamine + 1,4-diaminobutane
-
 Rattus norvegicus 5'-methylthioadenosine + spermidine
-
 ?
S-adenosyl-3-methylthio-1-propylamine + 1,5-diaminopentane
-
 Rattus norvegicus 5'-methylthioadenosine + N-(3-aminopropyl)-1,5-diaminopentane
-
 ?