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Literature summary for 2.5.1.16 extracted from

  • Caruso, A.; Pellati, A.; Bosi, G.; Arena, N.; Stabellini, G.
    Effects of spermidine synthase inhibition on cytoskeletal organization in cultured chick embryo fibroblasts (1994), Eur. J. Histochem., 38, 245-252.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
bis-cyclohexylammonium sulfate in vitro, 0.2 mM provokes strong decrease in cellular spermidine content, inhibition in cell growth, decrease in DNA synthesis, alterations in cell morphology, disorganization of microfilaments and changes in microtubule network structure, impairs the rate of microtubule reappearance after disruption with colchicine, alterations are prevented with spermidine addition Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
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chicken
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Source Tissue

Source Tissue Comment Organism Textmining
fibroblast embryo, 7 days old Gallus gallus
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