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Literature summary for 2.5.1.18 extracted from
- Inhibition of glutathione-S-transferase from Plasmodium yoelii by protoporphyrin IX, cibacron blue and menadione: implications and therapeutic benefits (2008), Parasitol. Res., 102, 805-807.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-methyl-1,4-naphthoquinone | 3.9% to 43.2% inhibition at 0.025 mM to 0.2 mM | Plasmodium yoelii |  |
| Cibacron blue | 94.3% inhibition at 0.064 mM | Plasmodium yoelii | |
| protoporphyrin IX | 31.3% to 85.6% inhibition at 0.00025 mM to 0.25 mM | Plasmodium yoelii | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Plasmodium yoelii | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Plasmodium yoelii | Q7REH6 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Plasmodium yoelii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione + 1-chloro-2,4-dinitrobenzene | - |
Plasmodium yoelii | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glutathione S-transferase | - |
Plasmodium yoelii |
| GST1 | - |
Plasmodium yoelii |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0004 | - |
Cibacron blue | - |
Plasmodium yoelii | |
| 0.013 | - |
protoporphyrin IX | - |
Plasmodium yoelii | |
| 0.08 | - |
2-methyl-1,4-naphthoquinone | - |
Plasmodium yoelii | |
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