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Literature summary for 2.5.1.18 extracted from
- Novel omega glutathione S-transferases in disk abalone: Characterization and protective roles against environmental stress (2009), Comp. Biochem. Physiol. C, 150, 558-568.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| HdGSTO1 and HdGSTO2, DNA and amino acid sequence determination and analysis, expression analysis and phylogenetic analysis | Haliotis discus discus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 26900 | - |
x * 27400, HdGSTO1, sequence calculation, x * 26900, HdGSTO2, sequence calculation | Haliotis discus discus |
| 27400 | - |
x * 27400, HdGSTO1, sequence calculation, x * 26900, HdGSTO2, sequence calculation | Haliotis discus discus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Haliotis discus discus | - |
two omega GST genes, HdGSTO1 and HdGSTO2 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| digestive tract | HdGSTO1 and HdGSTO2 | Haliotis discus discus | - |
| gill | HdGSTO1 | Haliotis discus discus | - |
| gonad | HdGSTO1 and HdGSTO2 | Haliotis discus discus | - |
| additional information | HdGSTO1 mRNA is expressed ubiquitously with high levels in all examined tissues, while HdGSTO2 shows specific expression in gonad and digestive tract | Haliotis discus discus | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 27400, HdGSTO1, sequence calculation, x * 26900, HdGSTO2, sequence calculation | Haliotis discus discus |
| More | three-dimensional structure determination of HdGSTO1 and HdGSTO2 by homology modeling, overview | Haliotis discus discus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GST | - |
Haliotis discus discus |
| omega glutathione S-transferase | - |
Haliotis discus discus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Haliotis discus discus |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 15 | 45 | - |
Haliotis discus discus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
assay at | Haliotis discus discus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Haliotis discus discus | expression of HdGSTO1, and also of HdGSTO2 in other tissues but to a lower extent, in gills is highgly upregulated by heat shock, heavy metals and endocrinedisrupting chemical exposure, e.g. by beta-naphthoflavone, benzo [alpha] pyrene, aroclor-1254, and tributyltin chloride | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | HdGSTO1 might play important protective roles against environmental stress. Under thermal stress, HdGSTO2 expression is repressed in a time-dependent pattern, implying different physiological roles of the isozymes under stress | Haliotis discus discus |
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Release 2023.1 (January 2023)
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