Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(Z)-2-farnesyl-3-methylbutenedioic acid dilithium salt | i.e. SG-129, 25% inhibition at 0.18 mM, noncompetitive | Hevea brasiliensis | |
(Z)-2-farnesyl-3-methylbutenedioic acid dilithium salt | i.e. SG-129, 27-48% inhibition at 0.18 mM, competitive | Parthenium argentatum | |
(Z)-2-octyl-3-methylbutenedioic acid dilithium salt | i.e. SG-296, 40% inhibition at 0.18 mM | Hevea brasiliensis | |
alpha-hydroxyfarnesylphosphonic acid | i.e. HFPA, competitive | Hevea brasiliensis | |
alpha-hydroxyfarnesylphosphonic acid | i.e. HFPA, competitive | Parthenium argentatum | |
chaetomellic acid | inhibitory in 20fold molar excess over isopentenyl diphosphate or 200fold molar excess over farnesyl diphosphate, competitive | Hevea brasiliensis | |
chaetomellic acid | 27-48% inhibition at 0.18 mM, competitive | Parthenium argentatum | |
additional information | not inhibitory: (Z)-2-octyl-3-methylbutenedioic acid dilithium salt | Parthenium argentatum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hevea brasiliensis | - |
- |
- |
Parthenium argentatum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
isopentenyl diphosphate + farnesyl diphosphate | - |
Hevea brasiliensis | diphosphate + ? | - |
? | |
isopentenyl diphosphate + farnesyl diphosphate | - |
Parthenium argentatum | diphosphate + ? | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0088 | - |
chaetomellic acid | pH 7.5, 25°C | Parthenium argentatum | |
0.025 | - |
(Z)-2-farnesyl-3-methylbutenedioic acid dilithium salt | pH 7.5, 25°C | Parthenium argentatum | |
0.042 | - |
chaetomellic acid | pH 7.5, 25°C | Hevea brasiliensis | |
0.064 | - |
alpha-hydroxyfarnesylphosphonic acid | pH 7.5, 25°C | Hevea brasiliensis | |
0.14 | - |
(Z)-2-farnesyl-3-methylbutenedioic acid dilithium salt | pH 7.5, 25°C | Hevea brasiliensis | |
0.42 | - |
alpha-hydroxyfarnesylphosphonic acid | pH 7.5, 25°C | Parthenium argentatum |