Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.21 extracted from

  • Qureshi, A.A.; Beytia, E.D.; Porter, J.W.
    Squalene synthetase. I. Dissociation and reassociation of enzyme complex (1972), Biochem. Biophys. Res. Commun., 48, 1123-1128.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
farnesyl diphosphate + farnesyl diphosphate
-
Saccharomyces cerevisiae diphosphate + presqualene diphosphate
-
?
farnesyl diphosphate + NAD(P)H
-
Saccharomyces cerevisiae squalene + diphosphate + NAD(P)+
-
?
presqualene diphosphate + NAD(P)H the polymeric form of the enzyme also catalyzes the reduction of presqualene diphosphate by NADPH to squalene Saccharomyces cerevisiae squalene + NAD(P)+ + diphosphate
-
?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Saccharomyces cerevisiae