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Literature summary for 2.5.1.21 extracted from
- Redirection of flux through the FPP branch-point in Saccharomyces cerevisiae by down-regulating squalene synthase (2008), Biotechnol. Bioeng., 100, 371-378.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | downregulation of expression by replacing its native promoter with the methionine-repressible MET3 promoter. Under certain culture conditions amorphadiene production increases fivefold upon ERG9 repression. With increasing flux to amorphadiene, squalene and ergosterol production each decrease. The levels of these three metabolites are dependent not only upon the level of ERG9 repression, but also the timing of its repression relative to the induction of amorphadiene synthase and genes responsible for enhancing flux to farnesyl diphosphate | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Erg9 | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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