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Literature summary for 2.5.1.22 extracted from

  • Hannonen, P.; Jänne, J.; Raina, A.
    Partial purification and characterization of spermine synthase from rat brain (1972), Biochim. Biophys. Acta, 289, 225-231.
    View publication on PubMed
Search for more literature for 2.5.1.22

Inhibitors

Inhibitors Comment Organism Structure
putrescine
-
 Rattus norvegicus
spermine
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.005
-
 S-adenosylmethioninamine
-
 Rattus norvegicus
0.07
-
 spermidine
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no metal ion requirement Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Wistar
-
Rattus norvegicus Wistar
-
 Wistar
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.306
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosylmethioninamine + spermidine
-
 Rattus norvegicus 5'-methylthioadenosine + spermine
-
 ?
S-adenosylmethioninamine + spermidine
-
 Rattus norvegicus Wistar 5'-methylthioadenosine + spermine
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
 pI: 5 Rattus norvegicus
7.5 8.1
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
additional information no cofactor requirement Rattus norvegicus