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Literature summary for 2.5.1.26 extracted from

  • Brown, A.; Snyder, F.
    Alkyldihydroxyacetonephosphate synthase (1992), Methods Enzymol., 209, 377-384.
    View publication on PubMed

General Stability

General Stability Organism
sensitive to sulfhydryl reagents, dithiothreitol prevents oxidation Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
acyldihydroxyacetone phosphate high concentration, substrate inhibition Mus musculus
fatty acids competitive to fatty alcohols Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-acylglycerone 3-phosphate + long-chain alcohol Mus musculus forms the ether bond found in alkyl and alk-1-enyl glycerolipids alkylglycerone 3-phosphate + long-chain acid anion + H+
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Mus musculus

Reaction

Reaction Comment Organism Reaction ID
long-chain acylglycerone 3-phosphate + long-chain alcohol = long-chain alkylglycerone 3-phosphate + long-chain carboxylate mechanism Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
Ehrlich ascites carcinoma cell
-
Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.067
-
-
Mus musculus

Storage Stability

Storage Stability Organism
4°C, 20% ethylene glycol, solubilized and delipidated enzyme is stable for 1 month Mus musculus
in liquid N2, stable for 1 year Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-acylglycerone 3-phosphate + long-chain alcohol forms the ether bond found in alkyl and alk-1-enyl glycerolipids Mus musculus alkylglycerone 3-phosphate + long-chain acid anion + H+
-
?
additional information specific for acyldihydroxyacetone phosphate, acyldihydroxyacetone or 1-acyl-sn-glycerol 3-phosphate cannot substitute for acyldihydroxyacetone phosphate, the acyl group chain length in acyldihydroxyacetone phosphate should be C12 or longer Mus musculus additional information
-
?
palmitoyldihydroxyacetone phosphate + hexadecanol
-
Mus musculus 1-O-hexadecyldihydroxyacetone phosphate + palmitate
-
?