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Literature summary for 2.5.1.28 extracted from

  • Akhtar, T.A.; Matsuba, Y.; Schauvinhold, I.; Yu, G.; Lees, H.A.; Klein, S.E.; Pichersky, E.
    The tomato cis-prenyltransferase gene family (2013), Plant J., 73, 640-652.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene SlCPT1, located on chromosome 8, and other gene of the CPT gene family, DNA and amino acid sequence determination and analysis, phylogenetic analysis Solanum lycopersicum

Protein Variants

Protein Variants Comment Organism
additional information constitutive and trichome-specific RNAi-mediated knockdown of NDPS1, RNAi-mediated suppression of NDPS1 with greater reductions achieved with the general 35S promoter compared to the trichome-specific MKS1 promoter, phenotypes, overview Solanum lycopersicum

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast immunohistochemic analysis Solanum lycopersicum 9507
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dimethylallyl diphosphate + isopentenyl diphosphate Solanum lycopersicum
-
diphosphate + neryl diphosphate
-
?
dimethylallyl diphosphate + isopentenyl diphosphate Solanum lycopersicum MP-1
-
diphosphate + neryl diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Solanum lycopersicum C1K5M2 gene SlCPT1
-
Solanum lycopersicum MP-1 C1K5M2 gene SlCPT1
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information no expression of SlCPT1 in leaves, flowers, roots, and fruits Solanum lycopersicum
-
trichome type VI trichomes of leaves and stems, high expression level of SlCPT1 Solanum lycopersicum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dimethylallyl diphosphate + isopentenyl diphosphate
-
Solanum lycopersicum diphosphate + neryl diphosphate
-
?
dimethylallyl diphosphate + isopentenyl diphosphate dimethylallyl diphosphate is the preferred substrate Solanum lycopersicum diphosphate + neryl diphosphate
-
?
dimethylallyl diphosphate + isopentenyl diphosphate
-
Solanum lycopersicum MP-1 diphosphate + neryl diphosphate
-
?
dimethylallyl diphosphate + isopentenyl diphosphate dimethylallyl diphosphate is the preferred substrate Solanum lycopersicum MP-1 diphosphate + neryl diphosphate
-
?

Synonyms

Synonyms Comment Organism
NDPS1
-
Solanum lycopersicum
neryl diphosphate synthase
-
Solanum lycopersicum
short-chain cis-prenyldiphosphate synthase
-
Solanum lycopersicum
short-chain CPT
-
Solanum lycopersicum

General Information

General Information Comment Organism
evolution gene SlCPT1 encoding the NDPS1 belongs to the CPT gene family. All the short-chain CPT genes from tomato, i.e. SlCPT1, SlCPT2 and SlCPT6, are closely linked to terpene synthase gene clusters. NDPS1 belongs to the short-chain cis-prenyldiphosphate synthases Solanum lycopersicum
malfunction RNAi-mediated suppression of NDPS1 leads to a large decrease in beta-phellandrene, which is produced from neryl diphosphate Solanum lycopersicum
physiological function NDPS1 catalyzes the formation of NPP, which is used as a substrate by beta-phellandrene synthase 1, PHS1, to produce beta-phellandrene and several other monoterpenes Solanum lycopersicum