Literature summary for 2.5.1.29 extracted from

K-M Chen, C.; Hudock, M.P.; Zhang, Y.; Guo, R.T.; Cao, R.; No, J.H.; Liang, P.H.; Ko, T.P.; Chang, T.H.; Chang, S.C.; Song, Y.; Axelson, J.; Kumar, A.; Wang, A.H.; Oldfield, E.
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation (2008), J. Med. Chem., 51, 5594-5607.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop method. Structures of a series of n-alkyl and dialkenyl bisphosphonates bound to GGPPS. The binding modes seen crystallographically can be well predicted computationally, facilitating the development of quantitative structure-activity models	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O95749	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Synonyms

Synonyms	Comment	Organism
geranylgeranyl diphosphate synthase	-	Homo sapiens
GGPPS	-	Homo sapiens

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Release 2023.1 (January 2023)