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Literature summary for 2.5.1.45 extracted from

  • Anke, S.; Niemuller, D.; Moll, S.; Hansch, R.; Ober, D.
    Polyphyletic origin of pyrrolizidine alkaloids within the Asteraceae. Evidence from differential tissue expression of homospermidine synthase (2004), Plant Physiol., 136, 4037-4047.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.45

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Eupatorium cannabinum

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Eupatorium cannabinum 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
spermidine + putrescine Eupatorium cannabinum first specific enzyme in the biosynthesis of the necine base moiety of pyrrolizidine alkaloids sym-homospermidine + propane-1,3-diamine
-
 ?
spermidine + putrescine Jacobaea vulgaris first specific enzyme in the biosynthesis of the necine base moiety of pyrrolizidine alkaloids sym-homospermidine + propane-1,3-diamine
-
 ?

Organism

Organism UniProt Comment Textmining
Eupatorium cannabinum
-
-
-
Jacobaea vulgaris
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Eupatorium cannabinum

Source Tissue

Source Tissue Comment Organism Textmining
root gene expression is restricted to young root. Expressed uniformly in all cells of the root cortex parenchyma, but not within the endodermis and exodermis Eupatorium cannabinum
-
root gene expression is restricted to young root. Expressed uniformly in all cells of the root cortex parenchyma, but not within the endodermis and exodermis Jacobaea vulgaris
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
spermidine + putrescine first specific enzyme in the biosynthesis of the necine base moiety of pyrrolizidine alkaloids Eupatorium cannabinum sym-homospermidine + propane-1,3-diamine
-
 ?
spermidine + putrescine first specific enzyme in the biosynthesis of the necine base moiety of pyrrolizidine alkaloids Jacobaea vulgaris sym-homospermidine + propane-1,3-diamine
-
 ?