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Literature summary for 2.5.1.46 extracted from
- Deoxyhypusine synthase activity is essential for cell viability in the yeast Saccharomyces cerevisiae (1998), J. Biol. Chem., 273, 1677-1683.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Saccharomyces cerevisiae |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| K308R/K350E | no activity | Saccharomyces cerevisiae |
| K308R/K350P | no activity | Saccharomyces cerevisiae |
| K308R/K350R | no activity | Saccharomyces cerevisiae |
| K350R | no activity | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| [eIF5A-precursor]-lysine + spermidine | - |
Saccharomyces cerevisiae | [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine | i.e. [eIF5A-precursor]-N6-(4-aminobutyl)lysine | ? |  |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Saccharomyces cerevisiae | |
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Release 2023.1 (January 2023)
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