Literature summary for 2.5.1.46 extracted from

Huang, J.K.; Tsai, S.; Huang, G.H.; Gowda, P.G.; Walzer, A.M.; Wen, L.
Higher activity of recombinant bovine deoxyhypusine synthase vs. human deoxyhypusine synthase (2004), Protein Expr. Purif., 35, 32-38.

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Cloned(Commentary)

Cloned (Comment)	Organism
subcloning of bovine and human DHS gene, overexpression in Escherichia coli	Homo sapiens
subcloning of bovine and human DHS gene, overexpression in Escherichia coli	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	Q6EWQ6	recombinant enzyme	-
Homo sapiens	-	recombinant enzyme	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[eIF5A-precursor]-lysine + spermidine	bovine enzyme is approximately 26times as effective as the human enzyme in catalyzing the reaction	Homo sapiens	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?
[eIF5A-precursor]-lysine + spermidine	bovine enzyme is approximately 26times as effective as the human enzyme in catalyzing the reaction	Bos taurus	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?

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Release 2023.1 (January 2023)