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Literature summary for 2.5.1.49 extracted from

  • Yamagata, S.; Takeshima, K.; Naiki, N.
    Evidence for the identity of O-acetylserine sulfhydrylase with O-acetylhomoserine sulfhydrylase in yeast (1974), J. Biochem., 75, 1221-1229.
    View publication on PubMed
Search for more literature for 2.5.1.49

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.12
-
 O-acetyl-L-serine
-
 Saccharomyces cerevisiae
6.67
-
 O-acetyl-L-homoserine
-
 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
O-acetyl-L-homoserine + H2S Saccharomyces cerevisiae
-
 L-homocysteine + acetic acid
-
 ?
O-acetyl-L-homoserine + methanethiol Saccharomyces cerevisiae
-
 L-methionine + acetate
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 baker's yeast
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.02
-
 substrate O-acetyl-L-serine Saccharomyces cerevisiae
6.88
-
 substrate O-acetyl-L-homoserine Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information O-acetyl-L-threonine, O-acetyl-L-tyrosine, O-acetyl-L-hydroxyproline and O-succinyl-DL-homoserine are no substrates Saccharomyces cerevisiae ?
-
 ?
O-acetyl-L-homoserine + ethyl mercaptan
-
 Saccharomyces cerevisiae L-ethionine + acetic acid
-
 ?
O-acetyl-L-homoserine + H2S
-
 Saccharomyces cerevisiae L-homocysteine + acetic acid
-
 ?
O-acetyl-L-homoserine + methanethiol relative activity 100% Saccharomyces cerevisiae L-methionine + acetic acid
-
 ?
O-acetyl-L-homoserine + methanethiol
-
 Saccharomyces cerevisiae L-methionine + acetate
-
 ?
O-acetyl-L-homoserine + methyl mercaptan
-
 Saccharomyces cerevisiae L-methionine + acetic acid
-
 ?
O-acetyl-L-serine + H2S
-
 Saccharomyces cerevisiae S-methylcysteine + ?
-
 ?
O-acetyl-L-serine + methanethiol reaction only in phosphate buffer, relative activity compared to O-acetyl-L-homoserine 14.8% Saccharomyces cerevisiae ?
-
 ?
O-acetyl-L-serine + methyl mercaptan
-
 Saccharomyces cerevisiae S-methylcysteine + ?
-
 ?

Synonyms

Synonyms Comment Organism
OAH
-
 Saccharomyces cerevisiae

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
40 65 activity decreases at about 40°C and is completely lost at 65°C Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.4
-
-
 Saccharomyces cerevisiae