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Literature summary for 2.5.1.90 extracted from

  • Okada, K.; Minehira, M.; Zhu, X.; Suzuki, K.; Nakagawa, T.; Matsuda, H.; Kawamukai, M.
    The ispB gene encoding octaprenyl diphosphate synthase is essential for growth of Escherichia coli (1997), J. Bacteriol., 179, 3058-3060.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information expression rescues an Escherichia coli chromosomal ispB disruptant Synechocystis sp. PCC 6803
additional information expression rescues an Escherichia coli chromosomal ispB disruptant Haemophilus influenzae

Organism

Organism UniProt Comment Textmining
Escherichia coli K-12 P0AD57
-
-
Haemophilus influenzae P44916
-
-
Synechocystis sp. PCC 6803
-
-
-

General Information

General Information Comment Organism
malfunction it is impossible to obtain an ispB deletion mutant unless the ispB gene or its homolog is supplied on a plasmid. The ispB gene is essential for the normal growth of Escherichia coli Escherichia coli
physiological function octaprenyl diphosphate synthase is responsible for the synthesis of the side chain of isoprenoid quinones Escherichia coli
physiological function the chromosomal ispB disrupted mutant cannot be isolated unless the ispB gene or its homolog is supplied on a plasmid. The chromosomal ispB disruptants that harbor plasmids carrying the ispB homologs from Haemophilus influenzae and Synechocystis sp. strain PCC6803 produce mainly ubiquinone 7 and ubiquinone 9, respectively Escherichia coli K-12